Overview Prime editing is an advanced genome editing technology poised to revolutionize gene therapy by providing a precise and versatile tool for genetic modification. Prime editing combines the CRISPR-Cas9 system with a reverse transcriptase enzyme to achieve highly accurate gene corrections without creating double-strand DNA...
Biotechnology
The Wild Classroom: Bridging Nature and Science in Pharmaceuticals
Overview The Wild Classroom is an engaging resource focusing on biology, conservation, and ecology. It provides a wide range of tools and resources for teachers, students, and parents alike. Their mission is to foster an appreciation for nature and wildlife, inspiring the next generation to...
AACR 2024 Epibiologics Advances Degraders of Membrane-bound Proteins: New Horizons in Targeted Therapy
Overview EpiBiologics, a one-year-old company, is making waves in targeted protein degradation. They aim to tackle membrane and extracellular proteins, which have been tough targets for drug developers. Ann Lee-Karlon, PhD, is leading the charge as CEO. With her experience at Genentech and Altos Labs,...
Arialys Therapeutics Raises $58M Seed Money to Target Autoimmune Neuropsychiatric Diseases: A Game-Changer in Pharma
Overview Arialys Therapeutics is advancing the field of neurological treatment by targeting autoimmune neuropsychiatric diseases. With $58 million in seed financing, the company has the support of several key investors. Founding investors include Avalon BioVentures, Catalys Pacific, MPM BioImpact, Johnson & Johnson Innovation—JJDC, Inc., and...
OCD Linked to Neurotransmitter Imbalance in Forebrain: Emerging Research Insights
Overview Researchers from the University of Cambridge have used advanced brain imaging to uncover a neurochemical imbalance in specific brain regions of patients with obsessive-compulsive disorder (OCD). By employing 7-Tesla Magnetic Resonance Spectroscopy (MRS), they identified disruptions in the balance of the neurotransmitters glutamate (Glu)...
Top 10 Best Selling Drugs: Breakthroughs in Pharmaceutical Sales
Overview The issue of high drug costs has brought both President Joe Biden and former President Donald Trump into a rare agreement. Both have taken significant actions they claim help control these costs, each pointing to their unique policy approaches as key achievements. For Biden,...
Prolonged Ketamine Exposure Leads to Changes in Dopamine System of Mouse Brain
Overview Ketamine, a drug with both clinical applications and recreational misuse, has significant effects on the brain. Columbia University researchers have found that prolonged exposure to ketamine causes structural changes in the brain’s dopamine system. This emphasizes the need to target specific brain areas for...
Gastric Cardia Cancer May Be Linked to Diet in Northern China: Emerging Insights
Overview Gastric cancer, particularly in the cardia region, remains a significant health issue in parts of northern China. The cardia, located where the esophagus meets the stomach, has shown high cancer rates in areas like the Taihang Mountains. Research links these high rates partly to...
Tome Biosciences Raises $213M to Commercialize MIT-Developed Genome Editing Tech
Overview With advancements in genome editing, new possibilities for treating challenging diseases are emerging. Tome Biosciences is at the forefront of these breakthroughs, leveraging cutting-edge technologies like CRISPR/Cas9. Funding and Partnerships: Recently, Tome Biosciences secured $213 million in Series A and B funding. This funding...
Wiping Out Zombie Cells in Fat: A New Frontier in Delaying Diabetes
Overview Research has shown that senescent cells, also known as “zombie cells,” accumulate in fat tissue and can contribute to obesity-related insulin resistance and diabetes. These cells stop dividing but don’t die off, instead secreting harmful inflammatory factors. Senescent cells are not only found in...