Overview Advancements in Neuronal Cell Cultures Neuronal cell cultures are essential in neuroscience research. They help researchers understand neuron function, study diseases, develop drugs, and assess neurotoxicity. Keeping neurons alive and functioning as they do in the brain has always been a challenge. Gibco B-27...
News
Novo Nordisk Expands Boston Area Research and Early Development for Innovative Solutions
Overview Novo Nordisk has traditional roots in diabetes care, which is personal for Jacob Petersen, DMSc, especially after his daughter’s diagnosis. Located in Lexington, MA, Novo Nordisk is surging ahead with its commitment to treating metabolic disorders and diabetes. Their efforts showcase advancements aimed at...
Sparda: A Programmable Nucleic Acid Targeting Technology Like CRISPR Shaping Biomedical Advancements
Overview Researchers from the Russian Academy of Sciences have developed a new programmable tool for targeting nucleic acids, based on a prokaryotic immune defense system. This innovative system is different from the well-known CRISPR-Cas systems. By re-engineering prokaryotic Argonautes (pAgos) to make use of RNA...
Transient Transfection of Suspension Cells: A Quick and Effective Method for High-Yield Protein Production
Overview For efficient biotherapeutic protein production, especially as drug targets grow more intricate, mammalian cell systems have become the go-to resource. The capabilities of these systems, such as proper protein folding, assembly, and post-translational modifications, make them ideal for producing fully bioreactive end products. Suspension...
Why Antihistamines Often Don’t Work: Understanding Severe Itch Control
Overview Researchers have found that allergens in the environment can cause episodes of severe itching in eczema patients. This itching often doesn’t respond to common antihistamines because the itch signals are transmitted through a previously unknown pathway. This finding opens up new possibilities for developing...
ASGCT 2024: Moonwalk Biosciences Presents Advanced Multiplex Epigenetic Engineering Platform
Overview Moonwalk Biosciences began operations in 2024, starting strong in the field of epigenome editing. Named after the famous 1980s dance, not moon exploration, the name reflects their unique approach. According to Alex Aravanis, MD, PhD, the company’s CEO and co-founder, the name symbolizes a...
Roche to Acquire Carmot Therapeutics for Up to $3.1B in Landmark Pharma Deal
Overview Roche, a prominent player in the pharmaceutical industry, has announced its acquisition of Carmot Therapeutics for an amount that could reach up to $3.1 billion. This acquisition signals Roche’s renewed interest in the rapidly expanding market of obesity treatments. Carmot Therapeutics, based in Berkeley,...
Dual CRISPR RNA Method May Help Treat Duchenne Muscular Dystrophy: A Scientific Breakthrough
Overview Recent advancements have demonstrated the potential of using dual CRISPR RNA methods to restore dystrophin protein function in cells derived from Duchenne muscular dystrophy (DMD) patients. Researchers from Kyoto University, in their study titled, “Dual CRISPR-Cas3 system for inducing multi-exon skipping in DMD patient-derived...
China Upholds Key CVC CRISPR Patent: Major Win for ERS Genomics
Overview The Chinese National Intellectual Property Administration (CNIPA) has upheld a pivotal patent within the CRISPR/Cas9 portfolio. This patent is a significant part of the intellectual property owned by Nobel Laureate Emmanuelle Charpentier, the University of California, and the University of Vienna, collectively known as...
Top 10 U.S. Biopharma Clusters Transforming Life Sciences
Overview Top-tier biopharma clusters thrive because they combine exceptional resources and talent. These regions boast powerhouse universities, dynamic research institutes, and innovative companies capable of transforming investment into profits. They attract significant public and private funding, including billions in venture capital (VC) and establish extensive...