Overview Embedding fluorescent synthetic dyes used for medical imaging into cancer cell membranes and inducing rapid vibrations causes necrosis. These vibrating aminocyanines achieve whole-molecule vibrations in under a picosecond, disrupting cellular processes at low light levels or concentrations. Known as the “molecular jackhammer” technique, researchers...
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Top 20 Biotech Accelerators and Incubators Revolutionizing the Pharma Industry
Overview Startups in the biotech world face specific challenges that can be navigated with the right support. Accelerators and incubators play a key role in offering resources to help these startups thrive. They provide not just funding but also mentorship, networking opportunities, and access to...
Recibiopharm Agrees to Tech Transfer and Manufacture of Acuitas’ LNP Formulations: Empowering Pharma Innovation
Overview ReciBioPharm and Acuitas Therapeutics are expanding their partnership, aiming to enhance CGMP manufacturing and technology transfer for mRNA-based therapeutics and vaccines. This collaboration targets customers licensing Acuitas’ lipid nanoparticle (LNP) formulations. Beginning in May 2022, ReciBioPharm, previously known as Arranta Bio, has worked with...
Top 10 Companies Leveraging Gene Editing: Innovations in Pharma
Overview Gene editing has become one of the most exciting fields in modern science, with companies like CRISPR Therapeutics, Editas Medicine, and Intellia Therapeutics leading the charge. These companies are developing therapies using advanced gene-editing technologies to treat a range of diseases. Despite some hiccups,...
Exscientia Fires CEO for Inappropriate Relationships with Employees: Impact on Pharmaceutical Leadership
Overview Exscientia has recently made significant leadership changes following the termination of its founder and former CEO, Andrew Hopkins, PhD. Hopkins was dismissed after the company’s board determined that he had inappropriate relationships with two employees, which went against the company’s values. This decision was...
e-cigarette Nicotine Appears to Hamper Mucus Clearance from Airways: Implications for Respiratory Health
Overview Nicotine-containing electronic cigarette (e-cigarette) vapor has been reported to impact mucus clearance in the airways. Research from several institutions including the University of Kansas, University of Miami, and Mt. Sinai Medical Center highlighted how e-cigarette vapor affects the movement of mucus, also known as...
Pfizer Pursues Vaccine R&D Expansion: New Labs, Cutting-Edge Tech, and Future Innovations
Overview Pfizer’s history with vaccine development stretches back many years, boasting numerous milestones, including the first drug approval by the FDA and the collaboration with BioNTech on the initial COVID-19 vaccine. Located about 25 miles northwest of New York City, their Pearl River site has...
ASGCT 2024: Saliogens’ Nonviral In Vivo Gene Insertion Technology Takes Preclinical Strides
Overview Jason F. Cole has been a key player in gene therapy for over a decade. His time at Bluebird involved pioneering the first generation of gene therapies, generally delivered via lentivirus in an ex vivo setup. Cole’s journey included steering advanced technology through early...
White Blood Cell and Platelet Trajectories: Key Indicators of Inflammation Recovery
Overview Trauma, infections, and other pathological conditions kickstart inflammation, the body’s first defense mechanism. Immune cells rush to the injury site to begin repairs, hoping to curb further damage. A new study by researchers at Harvard Medical School and Massachusetts General Hospital sheds light on...
Cell Therapy Manufacturing for Age-Related Diseases: Innovations and Challenges
Overview Multiply Labs and Retro Biosciences have partnered to tackle age-related diseases using state-of-the-art robotics. With this agreement, Multiply Labs will automate Retro’s manufacturing process to target the cellular drivers of aging. This collaboration marks the first commercial sale of Multiply Labs’ robotic system, which...