Pointe Scientific

Overview Recent advancements have demonstrated the potential of using dual CRISPR RNA methods to restore dystrophin protein function in cells derived from Duchenne muscular dystrophy (DMD) patients. Researchers from Kyoto University, in their study titled, “Dual CRISPR-Cas3 system for inducing multi-exon skipping in DMD patient-derived...

Overview Roche, a prominent player in the pharmaceutical industry, has announced its acquisition of Carmot Therapeutics for an amount that could reach up to $3.1 billion. This acquisition signals Roche’s renewed interest in the rapidly expanding market of obesity treatments. Carmot Therapeutics, based in Berkeley,...

Overview Moonwalk Biosciences began operations in 2024, starting strong in the field of epigenome editing. Named after the famous 1980s dance, not moon exploration, the name reflects their unique approach. According to Alex Aravanis, MD, PhD, the company’s CEO and co-founder, the name symbolizes a...

Overview Researchers have found that allergens in the environment can cause episodes of severe itching in eczema patients. This itching often doesn’t respond to common antihistamines because the itch signals are transmitted through a previously unknown pathway. This finding opens up new possibilities for developing...

Overview For efficient biotherapeutic protein production, especially as drug targets grow more intricate, mammalian cell systems have become the go-to resource. The capabilities of these systems, such as proper protein folding, assembly, and post-translational modifications, make them ideal for producing fully bioreactive end products. Suspension...

Overview Researchers at the Keck School of Medicine at USC have made significant progress in understanding how lizards regenerate their tails, focusing on both fibroblasts and septoclasts. Lizards have a unique ability to rebuild cartilage that replaces bone in their regenerated tails. This ability stands...

Overview Senescent cells are a significant aspect of aging and associated diseases like cancer, diabetes, cardiovascular disease, and Alzheimer’s. Senolytics, compounds that target and induce apoptosis in senescent cells, have shown promise but often suffer from low bioavailability and adverse side effects. A groundbreaking study...

Overview Cytiva and Pall’s life sciences business have joined forces under the Cytiva brand, becoming a significant player with 16,000 associates across 40 countries. Emmanuel Ligner, the Danaher group executive, president, and CEO of Cytiva, notes that this union aims to tackle major biotechnology challenges...

Overview Merger of Senda Biosciences and Laronde Senda Biosciences and Laronde, two of Flagship’s innovative companies, recently merged to form Sail Biomedicines. This move aims to create programmable medicines that revolutionize patient care. Led by Guillaume Pfefer, the merger brings together the strengths of both...

Overview Artificial intelligence (AI) and machine learning (ML) are revolutionizing drug discovery, substituting traditional high throughput screening (HTS) with computational methods. Conventional HTS fails to assess over 99% of commercially available molecules, significantly limiting the chemical search space. Atomwise, through its AIMS (Artificial Intelligence Molecular...